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Docetaxel induces Bcl-2- and pro-apoptotic caspase-independent death of human prostate cancer DU145 cells

Docetaxel is a useful chemotherapeutic agent for the first-line treatment of hormone-refractory prostate cancer. Abnormal expression of Bcl-2 is commonly found in cancer cells, which increases their anti-apoptotic potency and chemo-resistance. We investigated the effects of Bcl-2 expression status o...

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Detalles Bibliográficos
Autores principales: OGURA, TAKEHARU, TANAKA, YOSHIYUKI, TAMAKI, HIROKI, HARADA, MAMORU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864052/
https://www.ncbi.nlm.nih.gov/pubmed/27082738
http://dx.doi.org/10.3892/ijo.2016.3482