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Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

AIM: DNA methylation is the best known epigenetic mark. Cancer and other pathologies show an altered DNA methylome. However, delivering complete DNA methylation maps is compromised by the price and labor-intensive interpretation of single nucleotide methods. MATERIAL & METHODS: Following the suc...

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Detalles Bibliográficos
Autores principales: Moran, Sebastian, Arribas, Carles, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864062/
https://www.ncbi.nlm.nih.gov/pubmed/26673039
http://dx.doi.org/10.2217/epi.15.114