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Stable Translocation Intermediates Jam Global Protein Export in Plasmodium falciparum Parasites and Link the PTEX Component EXP2 with Translocation Activity

Protein export is central for the survival and virulence of intracellular P. falciparum blood stage parasites. To reach the host cell, exported proteins cross the parasite plasma membrane (PPM) and the parasite-enclosing parasitophorous vacuole membrane (PVM), a process that requires unfolding, sugg...

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Detalles Bibliográficos
Autores principales: Mesén-Ramírez, Paolo, Reinsch, Ferdinand, Blancke Soares, Alexandra, Bergmann, Bärbel, Ullrich, Ann-Katrin, Tenzer, Stefan, Spielmann, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864081/
https://www.ncbi.nlm.nih.gov/pubmed/27168322
http://dx.doi.org/10.1371/journal.ppat.1005618