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Histone deacetylase inhibitor-induced cell death in bladder cancer is associated with chromatin modification and modifying protein expression: A proteomic approach

The Cancer Genome Atlas (TCGA) project recently identified the importance of mutations in chromatin remodeling genes in human carcinomas. These findings imply that epigenetic modulators might have a therapeutic role in urothelial cancers. To exploit histone deacetylases (HDACs) as targets for cancer...

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Detalles Bibliográficos
Autores principales: LI, QINGDI QUENTIN, HAO, JIAN-JIANG, ZHANG, ZHENG, HSU, IAWEN, LIU, YI, TAO, ZHEN, LEWI, KEIDREN, METWALLI, ADAM R., AGARWAL, PIYUSH K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864178/
https://www.ncbi.nlm.nih.gov/pubmed/27082124
http://dx.doi.org/10.3892/ijo.2016.3478