The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function

TORC1 is a master regulator of metabolism in eukaryotes that responds to multiple upstream signaling pathways. The GATOR complex is a newly defined upstream regulator of TORC1 that contains two sub-complexes, GATOR1, which inhibits TORC1 activity in response to amino acid starvation and GATOR2, whic...

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Detalles Bibliográficos
Autores principales: Cai, Weili, Wei, Youheng, Jarnik, Michal, Reich, John, Lilly, Mary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864241/
https://www.ncbi.nlm.nih.gov/pubmed/27166823
http://dx.doi.org/10.1371/journal.pgen.1006036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864241/
https://www.ncbi.nlm.nih.gov/pubmed/27166823
http://dx.doi.org/10.1371/journal.pgen.1006036

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