Degenerin channel activation causes caspase‐mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle

BACKGROUND: Declines in skeletal muscle structure and function are found in various clinical populations, but the intramuscular proteolytic pathways that govern declines in these individuals remain relatively poorly understood. The nematode Caenorhabditis elegans has been developed into a model for...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaffney, Christopher J., Shephard, Freya, Chu, Jeff, Baillie, David L., Rose, Ann, Constantin‐Teodosiu, Dumitru, Greenhaff, Paul L., Szewczyk, Nathaniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864282/
https://www.ncbi.nlm.nih.gov/pubmed/27493871
http://dx.doi.org/10.1002/jcsm.12040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864282/
https://www.ncbi.nlm.nih.gov/pubmed/27493871
http://dx.doi.org/10.1002/jcsm.12040

Ejemplares similares