Effect of the specific proteasome inhibitor bortezomib on cancer‐related muscle wasting

BACKGROUND: Muscle wasting, a prominent feature of cancer cachexia, is mainly caused by sustained protein hypercatabolism. The enhanced muscle protein degradation rates rely on the activity of different proteolytic systems, although the Adenosine triphosphate (ATP)‐ubiquitin‐proteasome‐dependent pat...

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Detalles Bibliográficos
Autores principales: Penna, Fabio, Bonetto, Andrea, Aversa, Zaira, Minero, Valerio Giacomo, Rossi Fanelli, Filippo, Costelli, Paola, Muscaritoli, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864285/
https://www.ncbi.nlm.nih.gov/pubmed/27239411
http://dx.doi.org/10.1002/jcsm.12050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864285/
https://www.ncbi.nlm.nih.gov/pubmed/27239411
http://dx.doi.org/10.1002/jcsm.12050

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