Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect

The most common cystic fibrosis (CF) causing mutation, deletion of phenylalanine 508 (ΔF508 or Phe508del), results in functional expression defect of the CF transmembrane conductance regulator (CFTR) at the apical plasma membrane (PM) of secretory epithelia, which is attributed to the degradation of...

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Detalles Bibliográficos
Autores principales: Veit, Guido, Oliver, Kathryn, Apaja, Pirjo M., Perdomo, Doranda, Bidaud-Meynard, Aurélien, Lin, Sheng-Ting, Guo, Jingyu, Icyuz, Mert, Sorscher, Eric J., Hartman, John L., Lukacs, Gergely L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864299/
https://www.ncbi.nlm.nih.gov/pubmed/27168400
http://dx.doi.org/10.1371/journal.pbio.1002462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864299/
https://www.ncbi.nlm.nih.gov/pubmed/27168400
http://dx.doi.org/10.1371/journal.pbio.1002462

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