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Fluorogenic Substrates for In Situ Monitoring of Caspase-3 Activity in Live Cells
The in situ detection of caspase-3 activity has applications in the imaging and monitoring of multiple pathologies, notably cancer. A series of cell penetrating FRET-based fluorogenic substrates were designed and synthesised for the detection of caspase-3 in live cells. A variety of modifications of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864350/ https://www.ncbi.nlm.nih.gov/pubmed/27168077 http://dx.doi.org/10.1371/journal.pone.0153209 |