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A Modular Vaccine Development Platform Based on Sortase-Mediated Site-Specific Tagging of Antigens onto Virus-Like Particles

Virus-like particles (VLPs) can be used as powerful nanoscale weapons to fight against virus infection. In addition to direct use as vaccines, VLPs have been extensively exploited as platforms on which to display foreign antigens for prophylactic vaccination and immunotherapeutic treatment. Unfortun...

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Detalles Bibliográficos
Autores principales: Tang, Shubing, Xuan, Baoqin, Ye, Xiaohua, Huang, Zhong, Qian, Zhikang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864371/
https://www.ncbi.nlm.nih.gov/pubmed/27170066
http://dx.doi.org/10.1038/srep25741