Calorie restriction regulates circadian clock gene expression through BMAL1 dependent and independent mechanisms

Feeding behavior, metabolism and circadian clocks are interlinked. Calorie restriction (CR) is a feeding paradigm known to extend longevity. We found that CR significantly affected the rhythms in the expression of circadian clock genes in mice on the mRNA and protein levels, suggesting that CR repro...

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Detalles Bibliográficos
Autores principales: Patel, Sonal A., Velingkaar, Nikkhil, Makwana, Kuldeep, Chaudhari, Amol, Kondratov, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864379/
https://www.ncbi.nlm.nih.gov/pubmed/27170536
http://dx.doi.org/10.1038/srep25970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864379/
https://www.ncbi.nlm.nih.gov/pubmed/27170536
http://dx.doi.org/10.1038/srep25970

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