Cargando…

Menadione Suppresses Benzo(α)pyrene-Induced Activation of Cytochromes P450 1A: Insights into a Possible Molecular Mechanism

Oxidative reactions that are catalyzed by cytochromes P450 1A (CYP1A) lead to formation of carcinogenic derivatives of arylamines and polycyclic aromatic hydrocarbons (PAHs), such as the widespread environmental pollutant benzo(α)pyrene (BP). These compounds upregulate CYP1A at the transcriptional l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sidorova, Yulia A., Perepechaeva, Maria L., Pivovarova, Elena N., Markel, Arkady L., Lyakhovich, Vyacheslav V., Grishanova, Alevtina Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864395/ https://www.ncbi.nlm.nih.gov/pubmed/27167070 http://dx.doi.org/10.1371/journal.pone.0155135

Ejemplares similares

Association of cytochrome P450 genetic polymorphisms with neoadjuvant chemotherapy efficacy in breast cancer patients
por: Seredina, Tatyana A, et al.
Publicado: (2012)

Cytochrome P450 Monooxygenase-Mediated Metabolic Utilization of Benzo[a]Pyrene by Aspergillus Species
por: Ostrem Loss, Erin M., et al.
Publicado: (2019)

The Role of Aryl Hydrocarbon Receptor (AhR) in Brain Tumors
por: Perepechaeva, Maria L., et al.
Publicado: (2020)

Aryl Hydrocarbon Receptor in Oxidative Stress as a Double Agent and Its Biological and Therapeutic Significance
por: Grishanova, Alevtina Y., et al.
Publicado: (2022)

The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers
por: Šulc, Miroslav, et al.
Publicado: (2016)

Interaction of Thalassia testudinum Metabolites with Cytochrome P450 Enzymes and Its Effects on Benzo(a)pyrene-Induced Mutagenicity
por: Delgado-Roche, Livan, et al.
Publicado: (2020)

The Role of CYP3A in Health and Disease
por: Klyushova, Lyubov S., et al.
Publicado: (2022)

AhR and Wnt/β-Catenin Signaling Pathways and Their Interplay
por: Grishanova, Alevtina Y., et al.
Publicado: (2023)

AhR and HIF-1α Signaling Pathways in Benign Meningioma under Hypoxia
por: Perepechaeva, Maria L., et al.
Publicado: (2023)

Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase
por: Reed, Lindsay, et al.
Publicado: (2020)

Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice
por: Reed, Lindsay, et al.
Publicado: (2018)

Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems
por: Stiborová, Marie, et al.
Publicado: (2017)

Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine
por: Mrízová, Iveta, et al.
Publicado: (2016)

DhDIT2 Encodes a Debaryomyces hansenii Cytochrome P450 Involved in Benzo(a)pyrene Degradation—A Proposal for Mycoremediation
por: Padilla-Garfias, Francisco, et al.
Publicado: (2022)

NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1
por: Stiborová, Marie, et al.
Publicado: (2016)

Benzo[a]pyrene Cytotoxicity Tolerance in Testicular Sertoli Cells Involves Aryl-hydrocarbon Receptor and Cytochrome P450 1A1 Expression Deficiencies
por: Kim, Jin-Tac, et al.
Publicado: (2021)

NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene
por: Stiborová, Marie, et al.
Publicado: (2016)

Correction to NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene
por: Stiborová, Marie, et al.
Publicado: (2016)

UVA Photoirradiation of Methylated Benzo[a]pyrene and Benzo[e]pyrene leading to Induction of Lipid Peroxidation
por: Sáenz, Diógenes Herreño, et al.
Publicado: (2007)

Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2
por: Aimová, Dagmar, et al.
Publicado: (2008)

Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats
por: Stiborová, Marie, et al.
Publicado: (2018)

Bacillus subtilis is a Potential Degrader of Pyrene and Benzo[a]pyrene
por: Hunter, Rochelle D., et al.
Publicado: (2005)

Quantitation of exposure to benzo[a]pyrene with monoclonal antibodies.
por: Santella, R M, et al.
Publicado: (1985)

Changes of biomarkers with oral exposure to benzo(a)pyrene, phenanthrene and pyrene in rats
por: Kang, Hwan Goo, et al.
Publicado: (2007)

Free radicals of benzo(a)pyrene and derivatives.
por: Sullivan, P D
Publicado: (1985)

Cytotoxic effects of menadione on normal and cytochrome c-deficient yeast cells cultivated aerobically or anaerobically
por: Yamashoji, Shiro, et al.
Publicado: (2020)

GC-FID and HPLC-DAD Methods for the Determination of Menadione Sodium Bisulphite Directly and by Converting Menadione Sodium Bisulphite to Menadione in Pharmaceutical Preparation
por: Demirkaya-Miloglu, Fatma, et al.
Publicado: (2014)

The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy
por: Perepechaeva, M. L., et al.
Publicado: (2014)

Influence of Benzo(a)pyrene on Different Epigenetic Processes
por: Bukowska, Bożena, et al.
Publicado: (2021)

Benzo[a]pyrene and Benzo[k]fluoranthene in Some Processed Fish and Fish Products
por: Olatunji, Olatunde S., et al.
Publicado: (2015)

Different characteristics between menadione and menadione sodium bisulfite as redox mediator in yeast cell suspension
por: Yamashoji, Shiro
Publicado: (2016)

Formation and persistence of benzo(a)pyrene metabolite-DNA adducts.
por: Stowers, S J, et al.
Publicado: (1985)

Chemoresistance to Cancer Treatment: Benzo-α-Pyrene as Friend or Foe?
por: Dzobo, Kevin, et al.
Publicado: (2018)

Modulatory Effects of Silymarin on Benzo[a]pyrene-Induced Hepatotoxicity
por: Jee, Seung-Cheol, et al.
Publicado: (2020)

Poly(ADP-Ribose) Glycohydrolase (PARG) Silencing Suppresses Benzo(a)pyrene Induced Cell Transformation
por: Li, Xuan, et al.
Publicado: (2016)

Combination of carboplatin and intermittent normobaric hyperoxia synergistically suppresses benzo[a]pyrene-induced lung cancer
por: Lee, Hea Yon, et al.
Publicado: (2018)

Insight into the High-Efficiency Benzo(a)pyrene Degradation Ability of Pseudomonas benzopyrenica BaP3 and Its Application in the Complete Bioremediation of Benzo(a)pyrene
por: Dong, Xingchen, et al.
Publicado: (2023)

Metabolic Activation of Benzo[a]pyrene by Human Tissue Organoid Cultures
por: Caipa Garcia, Angela L., et al.
Publicado: (2022)

Benzo(a)pyrene Is Mutagenic in Mouse Spermatogonial Stem Cells and Dividing Spermatogonia
por: O’Brien, Jason M., et al.
Publicado: (2016)

Biotransformation of benzo[a]pyrene by Pannonibacter sp. JPA3 and the degradation mechanism through the initially oxidized benzo[a]pyrene-4,5-dihydrodiol to downstream metabolites
por: Jin, Jingnan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v2c3b5m078bmoq53272tfquhdj