nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs

The diversity of MTOR-regulated mRNA translation remains unresolved. Whereas ribosome-profiling suggested that MTOR almost exclusively stimulates translation of the TOP (terminal oligopyrimidine motif) and TOP-like mRNAs, polysome-profiling indicated that MTOR also modulates translation of mRNAs wit...

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Detalles Bibliográficos
Autores principales: Gandin, Valentina, Masvidal, Laia, Hulea, Laura, Gravel, Simon-Pierre, Cargnello, Marie, McLaughlan, Shannon, Cai, Yutian, Balanathan, Preetika, Morita, Masahiro, Rajakumar, Arjuna, Furic, Luc, Pollak, Michael, Porco, John A., St-Pierre, Julie, Pelletier, Jerry, Larsson, Ola, Topisirovic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864462/
https://www.ncbi.nlm.nih.gov/pubmed/26984228
http://dx.doi.org/10.1101/gr.197566.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864462/
https://www.ncbi.nlm.nih.gov/pubmed/26984228
http://dx.doi.org/10.1101/gr.197566.115

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