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Divergent modulation of Rho‐kinase and Ca(2+) influx pathways by Src family kinases and focal adhesion kinase in airway smooth muscle

BACKGROUND AND PURPOSE: The importance of tyrosine kinases in airway smooth muscle (ASM) contraction is not fully understood. The aim of this study was to investigate the role of Src‐family kinases (SrcFK) and focal adhesion kinase (FAK) in GPCR‐mediated ASM contraction and associated signalling eve...

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Detalles Bibliográficos
Autores principales: Shaifta, Yasin, Irechukwu, Nneka, Prieto‐Lloret, Jesus, MacKay, Charles E, Marchon, Keisha A, Ward, Jeremy P T, Knock, Greg A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864488/
https://www.ncbi.nlm.nih.gov/pubmed/26294392
http://dx.doi.org/10.1111/bph.13313