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Human serum antibodies against EBV latent membrane protein 1 cross-react with α-synuclein

OBJECTIVES: To identify the epitope on α-synuclein (α-syn) to which antibodies against the Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) bind and to determine whether antibodies targeting this mimicry domain are present in human sera. METHODS: Reactivity of the α-syn-cross-reacting anti-...

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Detalles Bibliográficos
Autores principales: Woulfe, John, Gray, Madison T., Ganesh, Munisha S., Middeldorp, Jaap M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864620/
https://www.ncbi.nlm.nih.gov/pubmed/27218119
http://dx.doi.org/10.1212/NXI.0000000000000239