Phosphopeptide binding by Sld3 links Dbf4‐dependent kinase to MCM replicative helicase activation

The initiation of eukaryotic DNA replication requires the assembly of active CMG (Cdc45‐MCM‐GINS) helicases at replication origins by a set of conserved and essential firing factors. This process is controlled during the cell cycle by cyclin‐dependent kinase (CDK) and Dbf4‐dependent kinase (DDK), an...

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Detalles Bibliográficos
Autores principales: Deegan, Tom D, Yeeles, Joseph TP, Diffley, John FX
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864760/
https://www.ncbi.nlm.nih.gov/pubmed/26912723
http://dx.doi.org/10.15252/embj.201593552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864760/
https://www.ncbi.nlm.nih.gov/pubmed/26912723
http://dx.doi.org/10.15252/embj.201593552

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