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Activation of MEK1/2‐ERK1/2 signaling during NNK‐induced lung carcinogenesis in female A/J mice

The extracellular signal‐regulated kinase 1/2 (ERK1/2) signaling pathway is activated by several growth factors and mitogens, and upregulation has been noted in many human cancers, including examples in the lung. In this study, to study the association of ERK1/2 activation with mutation of Kras enco...

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Detalles Bibliográficos
Autores principales: Yamakawa, Keiko, Yokohira, Masanao, Nakano, Yuko, Kishi, Sosuke, Kanie, Shohei, Imaida, Katsumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864820/
https://www.ncbi.nlm.nih.gov/pubmed/26864819
http://dx.doi.org/10.1002/cam4.652