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The mitochondrial calcium uniporter regulates breast cancer progression via HIF‐1α

Triple‐negative breast cancer (TNBC) represents the most aggressive breast tumor subtype. However, the molecular determinants responsible for the metastatic TNBC phenotype are only partially understood. We here show that expression of the mitochondrial calcium uniporter (MCU), the selective channel...

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Detalles Bibliográficos
Autores principales: Tosatto, Anna, Sommaggio, Roberta, Kummerow, Carsten, Bentham, Robert B, Blacker, Thomas S, Berecz, Tunde, Duchen, Michael R, Rosato, Antonio, Bogeski, Ivan, Szabadkai, Gyorgy, Rizzuto, Rosario, Mammucari, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864890/
https://www.ncbi.nlm.nih.gov/pubmed/27138568
http://dx.doi.org/10.15252/emmm.201606255