Frequent mutations in acetylation and ubiquitination sites suggest novel driver mechanisms of cancer

BACKGROUND: Discovery of cancer drivers is a major goal of cancer research. Driver genes and pathways are often predicted using mutation frequency, assuming that statistically significant recurrence of specific somatic mutations across independent samples indicates their importance in cancer. Howeve...

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Detalles Bibliográficos
Autores principales: Narayan, Soumil, Bader, Gary D., Reimand, Jüri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864925/
https://www.ncbi.nlm.nih.gov/pubmed/27175787
http://dx.doi.org/10.1186/s13073-016-0311-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864925/
https://www.ncbi.nlm.nih.gov/pubmed/27175787
http://dx.doi.org/10.1186/s13073-016-0311-2

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