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Immunocytochemical study of TOP2A and Ki-67 in cervical smears from women under routine gynecological care

BACKGROUND: Cervical cancer is one of the most common female cancers and is caused by human papillomavirus (HPV). Viral infection leads to cell cycle deregulation by inactivating p53 and retinoblastoma protein by viral oncoproteins E6 and E7, respectively. Then, nuclear proteins such as DNA topoisom...

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Detalles Bibliográficos
Autores principales:	Peres, Adrya Lúcia, Paz e Silva, Keilla Maria, de Araújo, Rosângela Ferreira Frade, de Lima Filho, José Luiz, de Melo Júnior, Mário Ribeiro, Martins, Danyelly Bruneska Gondim, de Pontes Filho, Nicodemos Teles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864931/ https://www.ncbi.nlm.nih.gov/pubmed/27175798 http://dx.doi.org/10.1186/s12929-016-0258-z

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