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Interplay between Fanconi anemia and homologous recombination pathways in genome integrity

The Fanconi anemia (FA) pathway plays a central role in the repair of DNA interstrand crosslinks (ICLs) and regulates cellular responses to replication stress. Homologous recombination (HR), the error‐free pathway for double‐strand break (DSB) repair, is required during physiological cell cycle prog...

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Detalles Bibliográficos
Autores principales: Michl, Johanna, Zimmer, Jutta, Tarsounas, Madalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865030/
https://www.ncbi.nlm.nih.gov/pubmed/27037238
http://dx.doi.org/10.15252/embj.201693860