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Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents

The 2-aminothiazole series has anti-bacterial activity against the important global pathogen Mycobacterium tuberculosis. We explored the nature of the activity by designing and synthesizing a large number of analogs and testing these for activity against M. tuberculosis, as well as eukaryotic cells....

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Detalles Bibliográficos
Autores principales: Kesicki, Edward A., Bailey, Mai A., Ovechkina, Yulia, Early, Julie V., Alling, Torey, Bowman, Julie, Zuniga, Edison S., Dalai, Suryakanta, Kumar, Naresh, Masquelin, Thierry, Hipskind, Philip A., Odingo, Joshua O., Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865136/
https://www.ncbi.nlm.nih.gov/pubmed/27171280
http://dx.doi.org/10.1371/journal.pone.0155209