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Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents
The 2-aminothiazole series has anti-bacterial activity against the important global pathogen Mycobacterium tuberculosis. We explored the nature of the activity by designing and synthesizing a large number of analogs and testing these for activity against M. tuberculosis, as well as eukaryotic cells....
Autores principales: | Kesicki, Edward A., Bailey, Mai A., Ovechkina, Yulia, Early, Julie V., Alling, Torey, Bowman, Julie, Zuniga, Edison S., Dalai, Suryakanta, Kumar, Naresh, Masquelin, Thierry, Hipskind, Philip A., Odingo, Joshua O., Parish, Tanya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865136/ https://www.ncbi.nlm.nih.gov/pubmed/27171280 http://dx.doi.org/10.1371/journal.pone.0155209 |
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