A Novel Method for Gene-Specific Enhancement of Protein Translation by Targeting 5’UTRs of Selected Tumor Suppressors

BACKGROUND: Translational control is a mechanism of protein synthesis regulation emerging as an important target for new therapeutics. Naturally occurring microRNAs and synthetic small inhibitory RNAs (siRNAs) are the most recognized regulatory molecules acting via RNA interference. Surprisingly, re...

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Detalles Bibliográficos
Autores principales: Master, Adam, Wójcicka, Anna, Giżewska, Kamilla, Popławski, Piotr, Williams, Graham R., Nauman, Alicja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865139/
https://www.ncbi.nlm.nih.gov/pubmed/27171412
http://dx.doi.org/10.1371/journal.pone.0155359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865139/
https://www.ncbi.nlm.nih.gov/pubmed/27171412
http://dx.doi.org/10.1371/journal.pone.0155359

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