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A Novel Method for Gene-Specific Enhancement of Protein Translation by Targeting 5’UTRs of Selected Tumor Suppressors
BACKGROUND: Translational control is a mechanism of protein synthesis regulation emerging as an important target for new therapeutics. Naturally occurring microRNAs and synthetic small inhibitory RNAs (siRNAs) are the most recognized regulatory molecules acting via RNA interference. Surprisingly, re...
Autores principales: | Master, Adam, Wójcicka, Anna, Giżewska, Kamilla, Popławski, Piotr, Williams, Graham R., Nauman, Alicja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865139/ https://www.ncbi.nlm.nih.gov/pubmed/27171412 http://dx.doi.org/10.1371/journal.pone.0155359 |
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