Lipopolysaccharide Is Cleared from the Circulation by Hepatocytes via the Low Density Lipoprotein Receptor

Sepsis is the leading cause of death in critically ill patients. While decreased Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) function improves clinical outcomes in murine and human sepsis, the mechanisms involved have not been fully elucidated. We tested the hypothesis that lipopolysacchar...

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Detalles Bibliográficos
Autores principales: Topchiy, Elena, Cirstea, Mihai, Kong, HyeJin Julia, Boyd, John H., Wang, Yingjin, Russell, James A., Walley, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865154/
https://www.ncbi.nlm.nih.gov/pubmed/27171436
http://dx.doi.org/10.1371/journal.pone.0155030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865154/
https://www.ncbi.nlm.nih.gov/pubmed/27171436
http://dx.doi.org/10.1371/journal.pone.0155030

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