Prevalence of Intrathecal Acyclovir Resistant Virus in Herpes Simplex Encephalitis Patients

Herpes simplex encephalitis (HSE) is a life-threatening complication of herpes simplex virus (HSV) infection. Acyclovir (ACV) is the antiviral treatment of choice, but may lead to emergence of ACV-resistant (ACV(R)) HSV due to mutations in the viral UL23 gene encoding for the ACV-targeted thymidine...

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Detalles Bibliográficos
Autores principales: Mitterreiter, Johanna G., Titulaer, Maarten J., van Nierop, Gijsbert P., van Kampen, Jeroen J. A., Aron, Georgina I., Osterhaus, Albert D. M. E., Verjans, Georges M. G. M., Ouwendijk, Werner J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865163/
https://www.ncbi.nlm.nih.gov/pubmed/27171421
http://dx.doi.org/10.1371/journal.pone.0155531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865163/
https://www.ncbi.nlm.nih.gov/pubmed/27171421
http://dx.doi.org/10.1371/journal.pone.0155531

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