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Prevalence of Intrathecal Acyclovir Resistant Virus in Herpes Simplex Encephalitis Patients
Herpes simplex encephalitis (HSE) is a life-threatening complication of herpes simplex virus (HSV) infection. Acyclovir (ACV) is the antiviral treatment of choice, but may lead to emergence of ACV-resistant (ACV(R)) HSV due to mutations in the viral UL23 gene encoding for the ACV-targeted thymidine...
Autores principales: | Mitterreiter, Johanna G., Titulaer, Maarten J., van Nierop, Gijsbert P., van Kampen, Jeroen J. A., Aron, Georgina I., Osterhaus, Albert D. M. E., Verjans, Georges M. G. M., Ouwendijk, Werner J. D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865163/ https://www.ncbi.nlm.nih.gov/pubmed/27171421 http://dx.doi.org/10.1371/journal.pone.0155531 |
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