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Maternal Smoking during Pregnancy and DNA-Methylation in Children at Age 5.5 Years: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study

Mounting evidence links prenatal exposure to maternal tobacco smoking with disruption of DNA methylation (DNAm) profile in the blood of infants. However, data on the postnatal stability of such DNAm signatures in childhood, as assessed by Epigenome Wide Association Studies (EWAS), are scarce. Object...

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Detalles Bibliográficos
Autores principales: Rzehak, Peter, Saffery, Richard, Reischl, Eva, Covic, Marcela, Wahl, Simone, Grote, Veit, Xhonneux, Annick, Langhendries, Jean-Paul, Ferre, Natalia, Closa-Monasterolo, Ricardo, Verduci, Elvira, Riva, Enrica, Socha, Piotr, Gruszfeld, Dariusz, Koletzko, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865176/
https://www.ncbi.nlm.nih.gov/pubmed/27171005
http://dx.doi.org/10.1371/journal.pone.0155554