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Development and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases

Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer that is associated with a poor prognosis and for which no targeted therapies currently exist. In order to improve preclinical testing for TNBC that relies primarily on using human xenografts in immunodeficient mice, we ha...

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Detalles Bibliográficos
Autores principales: Aprelikova, Olga, Tomlinson, Christine C., Hoenerhoff, Mark, Hixon, Julie A., Durum, Scott K., Qiu, Ting-hu, He, Siping, Burkett, Sandra, Liu, Zi-Yao, Swanson, Steven M., Green, Jeffrey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865188/
https://www.ncbi.nlm.nih.gov/pubmed/27171183
http://dx.doi.org/10.1371/journal.pone.0155262