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ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis

The endosomal sorting complexes required for transport (ESCRT) pathway facilitates multiple fundamental membrane remodeling events. Previously, we determined X-ray crystal structures of ESCRT-III subunit Snf7, the yeast CHMP4 ortholog, in its active and polymeric state (Tang et al., 2015). However,...

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Detalles Bibliográficos
Autores principales: Tang, Shaogeng, Buchkovich, Nicholas J, Henne, W Mike, Banjade, Sudeep, Kim, Yun Jung, Emr, Scott D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865371/
https://www.ncbi.nlm.nih.gov/pubmed/27074665
http://dx.doi.org/10.7554/eLife.15507