Neuronal and Astrocytic Monoacylglycerol Lipase Limit the Spread of Endocannabinoid Signaling in the Cerebellum123

Endocannabinoids are diffusible lipophilic molecules that may spread to neighboring synapses. Monoacylglycerol lipase (MAGL) is the principal enzyme that degrades the endocannabinoid 2-arachidonoylglycerol (2-AG). Using knock-out mice in which MAGL is deleted globally or selectively in neurons and a...

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Detalles Bibliográficos
Autores principales: Chen, Yao, Liu, Xiaojie, Vickstrom, Casey R., Liu, Michelle J., Zhao, Li, Viader, Andreu, Cravatt, Benjamin F., Liu, Qing-song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865651/
https://www.ncbi.nlm.nih.gov/pubmed/27182552
http://dx.doi.org/10.1523/ENEURO.0048-16.2016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865651/
https://www.ncbi.nlm.nih.gov/pubmed/27182552
http://dx.doi.org/10.1523/ENEURO.0048-16.2016

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