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Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation
Cytosine methylation, predominantly of the CpG sequence in vertebrates, is one of the major epigenetic modifications crucially involved in the control of gene expression. Due to the difficulty of reconstituting site‐specifically methylated nucleosomal DNA at crystallization quality, most structural...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865653/ https://www.ncbi.nlm.nih.gov/pubmed/27419055 http://dx.doi.org/10.1002/2211-5463.12064 |