Ringhalexin from Hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex

Anticoagulant therapy is used for the prevention and treatment of thromboembolic disorders. Blood coagulation is initiated by the interaction of factor VIIa (FVIIa) with membrane-bound tissue factor (TF) to form the extrinsic tenase complex which activates FX to FXa. Thus, it is an important target...

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Detalles Bibliográficos
Autores principales: Barnwal, Bhaskar, Jobichen, Chacko, Girish, Vallerinteavide Mavelli, Foo, Chun Shin, Sivaraman, J., Kini, R. Manjunatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865804/
https://www.ncbi.nlm.nih.gov/pubmed/27173146
http://dx.doi.org/10.1038/srep25935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865804/
https://www.ncbi.nlm.nih.gov/pubmed/27173146
http://dx.doi.org/10.1038/srep25935

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