Slug-upregulated miR-221 promotes breast cancer progression through suppressing E-cadherin expression

It is generally regarded that E-cadherin is downregulated during tumorigenesis via Snail/Slug-mediated E-cadherin transcriptional reduction. However, this transcriptional suppressive mechanism cannot explain the failure of producing E-cadherin protein in metastatic breast cancer cells after overexpr...

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Detalles Bibliográficos
Autores principales: Pan, Yi, Li, Jing, Zhang, Yaqin, Wang, Nan, Liang, Hongwei, Liu, Yuan, Zhang, Chen-Yu, Zen, Ke, Gu, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865839/
https://www.ncbi.nlm.nih.gov/pubmed/27174021
http://dx.doi.org/10.1038/srep25798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865839/
https://www.ncbi.nlm.nih.gov/pubmed/27174021
http://dx.doi.org/10.1038/srep25798

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