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Slug-upregulated miR-221 promotes breast cancer progression through suppressing E-cadherin expression
It is generally regarded that E-cadherin is downregulated during tumorigenesis via Snail/Slug-mediated E-cadherin transcriptional reduction. However, this transcriptional suppressive mechanism cannot explain the failure of producing E-cadherin protein in metastatic breast cancer cells after overexpr...
Autores principales: | Pan, Yi, Li, Jing, Zhang, Yaqin, Wang, Nan, Liang, Hongwei, Liu, Yuan, Zhang, Chen-Yu, Zen, Ke, Gu, Hongwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865839/ https://www.ncbi.nlm.nih.gov/pubmed/27174021 http://dx.doi.org/10.1038/srep25798 |
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