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Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons

Small soluble species of amyloid-beta (Aβ) formed during early peptide aggregation stages are responsible for several neurotoxic mechanisms relevant to the pathology of Alzheimer’s disease (AD), although their interaction with the neuronal membrane is not completely understood. This study quantifies...

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Detalles Bibliográficos
Autores principales: Ungureanu, Andreea-Alexandra, Benilova, Iryna, Krylychkina, Olga, Braeken, Dries, De Strooper, Bart, Van Haesendonck, Chris, Dotti, Carlos G., Bartic, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865860/
https://www.ncbi.nlm.nih.gov/pubmed/27173984
http://dx.doi.org/10.1038/srep25841