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Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons
Small soluble species of amyloid-beta (Aβ) formed during early peptide aggregation stages are responsible for several neurotoxic mechanisms relevant to the pathology of Alzheimer’s disease (AD), although their interaction with the neuronal membrane is not completely understood. This study quantifies...
Autores principales: | Ungureanu, Andreea-Alexandra, Benilova, Iryna, Krylychkina, Olga, Braeken, Dries, De Strooper, Bart, Van Haesendonck, Chris, Dotti, Carlos G., Bartic, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865860/ https://www.ncbi.nlm.nih.gov/pubmed/27173984 http://dx.doi.org/10.1038/srep25841 |
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