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Regulation of the T-box transcription factor Tbx3 by the tumour suppressor microRNA-206 in breast cancer

BACKGROUND: The Tbx3 transcription factor is over-expressed in breast cancer, where it has been implicated in proliferation, migration and regulation of the cancer stem cell population. The mechanisms that regulate Tbx3 expression in cancer have not been fully explored. In this study, we demonstrate...

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Detalles Bibliográficos
Autores principales: Amir, Sumaira, Simion, Catalina, Umeh-Garcia, Maxine, Krig, Sheryl, Moss, Tyler, Carraway, Kermit L, Sweeney, Colleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865973/
https://www.ncbi.nlm.nih.gov/pubmed/27100732
http://dx.doi.org/10.1038/bjc.2016.73