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Regulation of E3 ubiquitin ligase-1 (WWP1) by microRNA-452 inhibits cancer cell migration and invasion in prostate cancer

BACKGROUND: MicroRNA-224 (miR-224) and microRNA-452 (miR-452) are closely located on the human chromosome Xq28 region. miR-224 functions as a tumour suppressor by targeting tumour protein D52 (TPD52) in prostate cancer (PCa). Here, we aimed to investigate the functional significance of miR-452 in PC...

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Detalles Bibliográficos
Autores principales: Goto, Yusuke, Kojima, Satoko, Kurozumi, Akira, Kato, Mayuko, Okato, Atsushi, Matsushita, Ryosuke, Ichikawa, Tomohiko, Seki, Naohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865980/
https://www.ncbi.nlm.nih.gov/pubmed/27070713
http://dx.doi.org/10.1038/bjc.2016.95