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Microsatellite genotyping and genome-wide single nucleotide polymorphism-based indices of Plasmodium falciparum diversity within clinical infections

BACKGROUND: In regions where malaria is endemic, individuals are often infected with multiple distinct parasite genotypes, a situation that may impact on evolution of parasite virulence and drug resistance. Most approaches to studying genotypic diversity have involved analysis of a modest number of...

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Detalles Bibliográficos
Autores principales: Murray, Lee, Mobegi, Victor A., Duffy, Craig W., Assefa, Samuel A., Kwiatkowski, Dominic P., Laman, Eugene, Loua, Kovana M., Conway, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865991/
https://www.ncbi.nlm.nih.gov/pubmed/27176827
http://dx.doi.org/10.1186/s12936-016-1324-4