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Induction of the type I interferon response in neurological forms of Gaucher disease

BACKGROUND: Neuroinflammation is a key phenomenon in the pathogenesis of many neurodegenerative diseases. Understanding the mechanisms by which brain inflammation is engaged and delineating the key players in the immune response and their contribution to brain pathology is of great importance for th...

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Detalles Bibliográficos
Autores principales: Vitner, Einat B., Farfel-Becker, Tamar, Ferreira, Natalia Santos, Leshkowitz, Dena, Sharma, Piyush, Lang, Karl S., Futerman, Anthony H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866012/
https://www.ncbi.nlm.nih.gov/pubmed/27175482
http://dx.doi.org/10.1186/s12974-016-0570-2