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Target identification in Fusobacterium nucleatum by subtractive genomics approach and enrichment analysis of host-pathogen protein-protein interactions

BACKGROUND: Fusobacterium nucleatum, a well studied bacterium in periodontal diseases, appendicitis, gingivitis, osteomyelitis and pregnancy complications has recently gained attention due to its association with colorectal cancer (CRC) progression. Treatment with berberine was shown to reverse F. n...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Thotakura, Pragna Lakshmi, Tiwary, Basant Kumar, Krishna, Ramadas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866016/
https://www.ncbi.nlm.nih.gov/pubmed/27176600
http://dx.doi.org/10.1186/s12866-016-0700-0