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Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells

BACKGROUND: Pancreatic cancer is recognized as one of the most fatal tumors due to its aggressiveness and resistance to therapy. Statins were previously shown to inhibit the proliferation of cancer cells via various signaling pathways. In healthy tissues, statins activate the heme oxygenase pathway,...

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Detalles Bibliográficos
Autores principales: Vanova, K., Boukalova, S., Gbelcova, H., Muchova, L., Neuzil, J., Gurlich, R., Ruml, T., Vitek, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866069/
https://www.ncbi.nlm.nih.gov/pubmed/27175805
http://dx.doi.org/10.1186/s12885-016-2343-9