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Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells
BACKGROUND: Pancreatic cancer is recognized as one of the most fatal tumors due to its aggressiveness and resistance to therapy. Statins were previously shown to inhibit the proliferation of cancer cells via various signaling pathways. In healthy tissues, statins activate the heme oxygenase pathway,...
Autores principales: | Vanova, K., Boukalova, S., Gbelcova, H., Muchova, L., Neuzil, J., Gurlich, R., Ruml, T., Vitek, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866069/ https://www.ncbi.nlm.nih.gov/pubmed/27175805 http://dx.doi.org/10.1186/s12885-016-2343-9 |
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