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Subtilisin QK-2: secretory expression in Lactococcus lactis and surface display onto gram-positive enhancer matrix (GEM) particles

BACKGROUND: Purified from the supernatant of Bacillus subtilis QK02 culture broth, Subtilisin QK-2 is a type of effective thrombolytic reagent that has great exploitable potential. However, the unbearable flavor that occurs with fermentation and the complicated methods that are required to obtain pu...

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Detalles Bibliográficos
Autores principales: Mao, Ruifeng, Zhou, Kangping, Han, Zhenwei, Wang, Yefu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866291/
https://www.ncbi.nlm.nih.gov/pubmed/27176475
http://dx.doi.org/10.1186/s12934-016-0478-7