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Subtilisin QK-2: secretory expression in Lactococcus lactis and surface display onto gram-positive enhancer matrix (GEM) particles
BACKGROUND: Purified from the supernatant of Bacillus subtilis QK02 culture broth, Subtilisin QK-2 is a type of effective thrombolytic reagent that has great exploitable potential. However, the unbearable flavor that occurs with fermentation and the complicated methods that are required to obtain pu...
Autores principales: | Mao, Ruifeng, Zhou, Kangping, Han, Zhenwei, Wang, Yefu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866291/ https://www.ncbi.nlm.nih.gov/pubmed/27176475 http://dx.doi.org/10.1186/s12934-016-0478-7 |
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