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OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology

The improvement of preclinical cardiotoxicity testing, discovery of new ion-channel-targeted drugs, and phenotyping and use of stem cell-derived cardiomyocytes and other biologics all necessitate high-throughput (HT), cellular-level electrophysiological interrogation tools. Optical techniques for ac...

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Detalles Bibliográficos
Autores principales: Klimas, Aleksandra, Ambrosi, Christina M., Yu, Jinzhu, Williams, John C., Bien, Harold, Entcheva, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866323/
https://www.ncbi.nlm.nih.gov/pubmed/27161419
http://dx.doi.org/10.1038/ncomms11542