Cargando…

OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology

The improvement of preclinical cardiotoxicity testing, discovery of new ion-channel-targeted drugs, and phenotyping and use of stem cell-derived cardiomyocytes and other biologics all necessitate high-throughput (HT), cellular-level electrophysiological interrogation tools. Optical techniques for ac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klimas, Aleksandra, Ambrosi, Christina M., Yu, Jinzhu, Williams, John C., Bien, Harold, Entcheva, Emilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866323/ https://www.ncbi.nlm.nih.gov/pubmed/27161419 http://dx.doi.org/10.1038/ncomms11542

Ejemplares similares

OptoDyCE-plate as an affordable high throughput imager for all optical cardiac electrophysiology
por: Heinson, Yuli W., et al.
Publicado: (2023)

OptoGap is an optogenetics-enabled assay for quantification of cell–cell coupling in multicellular cardiac tissue
por: Boyle, Patrick M., et al.
Publicado: (2021)

All-Optical Electrophysiology Refines Populations of In Silico Human iPSC-CMs for Drug Evaluation
por: Paci, Michelangelo, et al.
Publicado: (2020)

Cardiac Optogenetics: Enhancement by All-trans-Retinal
por: Yu, Jinzhu, et al.
Publicado: (2015)

Portable low-cost macroscopic mapping system for all-optical cardiac electrophysiology
por: Heinson, Yuli W., et al.
Publicado: (2023)

CRISPRi Gene Modulation and All-Optical Electrophysiology in Post-Differentiated Human iPSC-Cardiomyocytes
por: Han, Julie L., et al.
Publicado: (2023)

All‐optical control of cardiac excitation: combined high‐resolution optogenetic actuation and optical mapping
por: Entcheva, Emilia, et al.
Publicado: (2016)

Computational Optogenetics: Empirically-Derived Voltage- and Light-Sensitive Channelrhodopsin-2 Model
por: Williams, John C., et al.
Publicado: (2013)

Linking brain activity across scales with simultaneous opto- and electrophysiology
por: Lewis, Christopher M., et al.
Publicado: (2023)

Opto-SICM framework combines optogenetics with scanning ion conductance microscopy for probing cell-to-cell contacts
por: Song, Qianqian, et al.
Publicado: (2023)

Sex-dependent transcription of cardiac electrophysiology and links to acetylation modifiers based on the GTEx database
por: Pressler, Michael P., et al.
Publicado: (2022)

Human iPSC-Cardiomyocytes as an Experimental Model to Study Epigenetic Modifiers of Electrophysiology
por: Pozo, Maria R., et al.
Publicado: (2022)

Artifact-free and high-temporal-resolution in vivo opto-electrophysiology with microLED optoelectrodes
por: Kim, Kanghwan, et al.
Publicado: (2020)

HectoSTAR μLED Optoelectrodes for Large‐Scale, High‐Precision In Vivo Opto‐Electrophysiology
por: Vöröslakos, Mihály, et al.
Publicado: (2022)

Optogenetic current in myofibroblasts acutely alters electrophysiology and conduction of co-cultured cardiomyocytes
por: Kostecki, Geran M., et al.
Publicado: (2021)

Opto-Box
por: Bertsche, David
Publicado: (2015)

Opto-Box
por: Bertsche, David, et al.
Publicado: (2015)

Compatible Photochromic Systems for Opto-electronic Applications
por: Szukalski, Adam, et al.
Publicado: (2021)

Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review
por: Müllenbroich, M. Caroline, et al.
Publicado: (2021)

Adeno-Associated Virus Mediated Gene Delivery: Implications for Scalable in vitro and in vivo Cardiac Optogenetic Models
por: Ambrosi, Christina M., et al.
Publicado: (2019)

A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes
por: Seibertz, Fitzwilliam, et al.
Publicado: (2022)

High-throughput optical sensing of peri-cellular oxygen in cardiac cells: system characterization, calibration, and testing
por: Li, Weizhen, et al.
Publicado: (2023)

High-throughput optical sensing of peri-cellular oxygen in cardiac cells: system characterization, calibration, and testing
por: Li, Weizhen, et al.
Publicado: (2023)

Opto-structural analysis
por: Pepi, John W
Publicado: (2018)

Opto-thermoelectric nanotweezers
por: Lin, Linhan, et al.
Publicado: (2018)

Opto-thermoelectric microswimmers
por: Peng, Xiaolei, et al.
Publicado: (2020)

Opto-refrigerative tweezers
por: Li, Jingang, et al.
Publicado: (2021)

Automated calibration of optoPlate LEDs to reduce light dose variation in optogenetic experiments
por: Grødem, Edvard OS, et al.
Publicado: (2020)

3rd Applied Optics and Opto-electronics Conference
por: Grattan, K T V
Publicado: (1995)

All-Optical Electrophysiology for High-Throughput Functional Characterization of a Human iPSC-Derived Motor Neuron Model of ALS
por: Kiskinis, Evangelos, et al.
Publicado: (2018)

Dyed Quinine
por: Warden, C. J. H.
Publicado: (1877)

Dyed Quinine
por: Browne, Jas.
Publicado: (1877)

Assembly of Dy(60) and Dy(30) cage-shaped nanoclusters
por: Luo, Zhi-Rong, et al.
Publicado: (2020)

Single Molecule Magnetism with Strong Magnetic Anisotropy and Enhanced Dy∙∙∙Dy Coupling in Three Isomers of Dy‐Oxide Clusterfullerene Dy(2)O@C(82)
por: Yang, Wei, et al.
Publicado: (2019)

Channelrhodopsin2 Current During the Action Potential: “Optical AP Clamp” and Approximation
por: Entcheva, Emilia, et al.
Publicado: (2014)

HectoSTAR μLED Optoelectrodes for Large‐Scale, High‐Precision In Vivo Opto‐Electrophysiology (Adv. Sci. 18/2022)
por: Vöröslakos, Mihály, et al.
Publicado: (2022)

Opto-electronic delay tubes
por: Gys, Thierry, et al.
Publicado: (1990)

Opto-Mechanical Systems Design
por: Yoder, Paul, et al.
Publicado: (2015)

Holographic opto-fluidic microscopy
por: Bishara, Waheb, et al.
Publicado: (2010)

ATLAS Pixel Opto-Electronics
por: Arms, Kregg E., et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_0vavckkeuhflpml24krkb0ek07