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PI3K p110β isoform synergizes with JNK in the regulation of glioblastoma cell proliferation and migration through Akt and FAK inhibition

BACKGROUND: Glioblastoma multiforme is the most aggressive malignant primary brain tumor, characterized by rapid growth and extensive infiltration to neighboring normal brain parenchyma. Both PI3K/Akt and JNK pathways are essential to glioblastoma cell survival, migration and invasion. Due to their...

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Detalles Bibliográficos
Autores principales:	Zhao, Hua-Fu, Wang, Jing, Jiang, Hao-Ran, Chen, Zhong-Ping, To, Shing-Shun Tony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866398/ https://www.ncbi.nlm.nih.gov/pubmed/27176481 http://dx.doi.org/10.1186/s13046-016-0356-5

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